Homologous IVF-ET

IN VITRO FERTILISATION AND EMBRYONIC TRANSFER

E-mail: info@procrea.ch | Tel.: +41 91 924 55 55 | FROM ITALY AT NO EXTRA COST: +39 02 600 630 41

IVF-ET - acronym of In Vitro Fertilisation and Embryo Transfer - is one of the most widely used techniques in assisted procreation. With homologous IVF-ET, the ovules and spermatozoa biologically belonging to the two components of the couple undergoing treatment are used.

IVF-ET was developed by Patrick Steptoe and Robert Edwards in the UK, the latter of whom was awarded the Nobel Prize for medicine in 2010.

According to the experience of ProCrea, the success rates of IVF-ET vary depending on the cause of infertility, the patient's age, and the values of the partner's seminal fluid. For all details please consult the relative Statistics section.

The homologous IVF-ET technique entails hormonal stimulation in the woman to induce the multiple growth of the follicles, then the picking up of the oocytes, their in vitro fertilisation with the spermatozoa of the partner, and the subsequent transfer of the embryos into the uterus. Any additional embryos are cryopreserved and remain available to the couple for any subsequent embryo transfers.

This procedure is indicated in cases of:
1. Previous failures with other assisted procreation techniques.
2. The presence of a fallopian tube factor.
3. The presence of a male factor (reduction of the concentration or motility of the spermatozoa).

IN DETAIL

1 OVARIAN STIMULATION
The follicles containing oocytes are induced by means of subcutaneous injections. The patient's ovarian response is monitored with ultrasound scans to evaluate the number and size of the follicles and blood samples taken to check the level of the hormones.

2 OVOCYTORY PICKUP
The oocytes are aspirated with a fine needle under transvaginal ultrasound. This operation lasts 10-15 minutes and is carried out in the operating room under sedation, without any pain. The patient is discharged approximately two hours afterwards.

3 IN VITRO FERTILISATION
The retrieved oocytes are placed on a culture plate together with the partner's sperm which has been prepared for fertilisation. After about 20 hours the development of the zygotes (pre-embryonic phase) is ascertained. The zygotes destined to be transferred into the uterus are left in culture for another 24-48 hours where they become real embryos. The average fertilisation rate is around 70%.

4 EMBRYO TRANSFER
The embryos are transferred into the uterine cavity via use of a thin catheter. The operation is rapid, painless and only lasts a few minutes. Normally only one or two embryos are transferred to avoid the risk of triple pregnancies.

HOW
With IVF-ET, in-vitro fertilisation of the eggs is carried out with the subsequent transfer of the embryo thus formed into the woman's uterus. Hormonal stimulation is foreseen for the woman in order to induce the growth of the follicles, after which the oocytes are picked up, their fertilisation carried out with the donor's sperm and finally followed by the transfer of the embryo. Any additional embryos are cryopreserved and remain available to the couple for any subsequent embryonic transfers.

WHEN
The treatment is divided into three phases, first the preparation with ovarian stimulation which leads to the oocyte pickup performed in the operating room under sedation and without any pain, then the actual in vitro fertilisation itself with the donor’s sperm, and finally the embryo transfer through a thin catheter, a quick and painless procedure.

COSTS
The costs of IVF-ET vary depending on the cycles required. The first cycle with the partner’s sperm costs 5,600 euro. The costs decrease as the treatment cycles progress. For all details regarding the therapy and everything included and not included in the costs please consult the relative Tariff section.

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