ProCrea | Heterologous FIVET with sperm donation| Lugano
ProCrea | Heterologous FIVET with sperm donation| Lugano
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Male heterologous IVF-ET


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Male heterologous IVF-ET is a technique based on the in-vitro fertilisation of the eggs with the subsequent transfer of the embryo into the patient's uterus which foresees the resorting to the use of donor sperm due to serious infertility problems of the male partner of the couple.

The male heterologous IVF-ET technique includes hormonal stimulation for the woman for inducing multiple growth of the follicles, followed by the collection of the oocytes, their in-vitro fertilisation with the sperm of a suitably selected donor, and the subsequent transfer of the embryos into the uterus. The additional embryos are cryopreserved (frozen) and remain available to the couple for any subsequent embryo transfers.

This is a procedure indicated in specific cases of severe male infertility, azoospermia (absence of spermatozoa) or failure of techniques using the partner’s sperm.

The main steps of this male heterologous fecundation technique include:

1 Ovarian stimulation
through subcutaneous injections, the growth of follicles containing oocytes is induced. The patient's ovarian response is monitored with ultrasound scans to evaluate the number and size of the follicles and blood samples taken to evaluate the level of the hormones.

2 Ovule pickup
the oocytes are aspirated using a fine needle. The operation takes place under sedation, in the operating room, and under transvaginal ultrasound control. It lasts a few minutes and the patient is discharged approximately two hours later.

3 In vitro fertilisation
the oocytes retrieved are placed in culture with the donor's sperm which has been prepared for obtaining fertilisation. After about 20 hours the development of the zygotes (pre-embryonic phase) is ascertained. The zygotes destined to be transferred into the uterus are left in cultivation for another 24-48 hours where they become real embryos. The average fertilisation rate is about 70%.

4 Embryo transfer
the embryos are transferred into the uterine cavity via use of a thin catheter. The operation is rapid, painless and only lasts a few minutes. Normally only one or two embryos are transferred to avoid the risk of triple pregnancies.

With IVF-ET, in-vitro fertilisation of the eggs is carried out via the subsequent transfer of the embryo thus formed into the woman's uterus. For the woman there is hormonal stimulation, in order to induce the growth of the follicles; the oocytes are then picked up and their fertilisation with the donor's sperm takes place, finally followed by the transfer of the embryo. The additional embryos are cryopreserved and remain available to the couple for any subsequent embryonic transfers.

The treatment is divided into three phases, first the preparation with ovarian stimulation which leads to the oocyte pickup performed in the operating room under sedation and without any pain, then the actual in vitro fertilisation itself with the donor’s sperm, and finally the embryo transfer through a thin catheter, a quick and painless procedure.

The costs of IVF-ET vary depending on the cycles required. The first cycle with the donor's sperm costs 5,900 euro. The costs decrease as the treatment cycles progress. For all details regarding the therapy and everything included and not included in the costs please consult the relative tariff section.

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